Predictors of Irregular Protrusion After Everolimus-Eluting Stent Implantation in Patients with Stable Coronary Artery Disease

DOI Web Site 参考文献23件
  • Taguchi Yuya
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Itoh Tomonori
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Sasaki Wataru
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Oda Hideto
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Uchimura Yohei
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Kaneko Kyosuke
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Sakamoto Tsubasa
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Goto Iwao
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Sakuma Masafumi
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Ishida Masaru
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Terashita Daisuke
    Division of Cardiology, Department of Internal Medicine, Kobe University Graduate School of Medicine
  • Otake Hiromasa
    Division of Cardiology, Department of Internal Medicine, Kobe University Graduate School of Medicine
  • Morino Yoshihiro
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Shinke Toshiro
    Division of Cardiovascular Medicine, Department of Internal Medicine, Showa University School of Medicine

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抄録

<p>This study aimed to investigate clinical and preintervention optical coherence tomography (OCT) findings to predict irregular protrusion (IRP) immediately after stent implantation.</p><p>We evaluated 84 lesions treated with cobalt-chromium everolimus-eluting stent (CoCr-EES) from the MECHANISM Elective study. Patients were divided into two groups according to the presence of IRP [IRP: n = 16, non-IRP: n = 68]. Optical coherence tomography images before intervention and immediately after stenting were evaluated with standard qualitative and quantitative OCT analyses.</p><p>Total cholesterol and the prevalence of ruptured plaque before intervention were significantly higher in the IRP group than in the non-IRP group [199 ± 37 mg/dL versus 176 ± 41 mg/dL; P = 0.022, 31% versus 7%; P = 0.008]. Total lipid length tended to be longer in the IRP group than in the non-IRP group [19.6 ± 9.2 mm versus 15.5 ± 9.3 mm; P = 0.090]. The prevalence of ruptured plaque, and total cholesterol levels were independent predictors of IRP immediately after stenting by multivariate logistic regression analysis [OR: 4.6, 95% confidence interval: 1.01-21.23, P = 0.048, OR: 1.02, 95% confidence interval: 1.00-1.03, P = 0.046]. IRP post-CoCr-EES implantation was completely resolved at follow-up OCT.</p><p>The prevalence of ruptured plaque before intervention and total cholesterol levels were independent predictors of IRP after CoCr-EES implantation in patients with stable coronary artery disease.</p>

収録刊行物

  • International Heart Journal

    International Heart Journal 63 (2), 210-216, 2022-03-30

    一般社団法人 インターナショナル・ハート・ジャーナル刊行会

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