Antimicrobial Resistance in Shiga Toxin-Producing Escherichia coli O157 and O26 Isolates from Beef Cattle

  • Sasaki Yoshimasa
    Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Usui Masaru
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Murakami Mariko
    Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Haruna Mika
    Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Kojima Akemi
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Asai Tetsuo
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry, and Fisheries, Japan
  • Yamada Yukiko
    Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry, and Fisheries, Japan

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タイトル別名
  • Antimicrobial Resistance in Shiga Toxin-Producing <i>Escherichia coli</i> O157 and O26 Isolates from Beef Cattle

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<p>This study was conducted to determine the prevalence of antimicrobial resistance in Shiga toxin-producing<tt> </tt>Escherichia coli<tt> </tt>(STEC) O157 (n<tt> </tt>= 241) and O26 (n<tt> </tt>= 11) isolated from beef cattle and to characterize their antimicrobial resistance profiles. Resistance to dihydrostreptomycin was detected most frequently (STEC O157, 9.5%; STEC O26, 54.5%), followed by resistance to oxytetracycline (7.9%; 45.5%) and ampicillin (5.4%; 36.4%). Resistance to one or more antimicrobial agents was detected in 13.3% (32/241) of the STEC O157 isolates and 54.5% (6/11) of the STEC O26 isolates. The antimicrobial resistance rate in the STEC O26 isolates was significantly higher than that in the STEC O157 isolates (P<tt> </tt>= 0.002, Fisher’s exact test). The antimicrobial resistance rate in the STEC O157 isolates possessing both<tt> </tt>stx1<tt> </tt>and<tt> </tt>stx2<tt> </tt>genes was 26.3% (15/57), while that in the isolates possessing<tt> </tt>stx2c<tt> </tt>gene alone was 3.9% (3/77). These findings suggest that the antimicrobial resistance in STEC O157 is associated with serogroups and the Shiga toxin genotype.</p>

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