Non-valvular Infective Endocarditis Caused by <i>Sarocladium kiliense</i> in an Immunocompromised Patient with Aplastic Anemia
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- Kitamura Hiroaki
- Department of Internal Medicine, Karatsu Red Cross Hospital, Japan
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- Kubota Yasushi
- Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan
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- Tomimasu Rika
- Department of Internal Medicine, Karatsu Red Cross Hospital, Japan
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- Akashi Michiaki
- Department of Pathology, Karatsu Red Cross Hospital, Japan
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- Mori Tadashi
- Department of Cardiology, Karatsu Red Cross Hospital, Japan
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- Mine Yutaro
- Department of Laboratory Medicine, Karatsu Red Cross Hospital, Japan
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- Ando Jun
- Department of Hematology, Juntendo University School of Medicine, Japan
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- Yamagata Murayama Somay
- Laboratory of Molecular Cell Biology, Graduate School of Pharmacy, Nihon University, Japan
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- Kimura Shinya
- Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan
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- Miyahara Masaharu
- Department of Internal Medicine, Karatsu Red Cross Hospital, Japan
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説明
<p>Sarocladium kiliense is ubiquitous in the human environment and is an emerging opportunistic pathogen, especially among immunocompromised hosts. A 77-year-old man diagnosed with aplastic anemia suffered from non-valvular endocarditis. After he passed away, fungal hyphae were observed in several lesions on a postmortem examination. Polymerase chain reaction (PCR) and a DNA sequence analysis revealed S. kiliense as the causative organism. This is the first case report of non-valvular fungal endocarditis caused by S. kiliense identified by PCR and a DNA sequence analysis in an immunocompromised patient. Although rare, invasive fungal infection caused by S. kiliense should be considered in immunocompromised hosts. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 61 (8), 1279-1283, 2022-04-15
一般社団法人 日本内科学会