A Case of Pappilary Renal Cell Caircinoma which Responded Well to the Combination Therapy of Ipilimumab and Nivolumab --A CASE REPORT--

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  • FUKATANI Yusuke
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • DAIZUMOTO Kei
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • KADORIKU Fumiya
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • YAMAMOTO Hiraku
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • SASAKI Yutaro
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • OZAKI Keisuke
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • UENO Yoshiteru
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • TUDA Megumi
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • KUSUHARA Yoshito
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • FUKAWA Tomoya
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • YAMAMOTO Yasuyo
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • YAMAGUCHI Kunihisa
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • TAKAHASHI Masayuki
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • KANAYAMA Hiroomi
    The Department of Urology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • NIKI Mariko
    The Department of Dermatology, Institute of Biomedical Sciences, Tokushima University Graduate School
  • UEHARA Hisanori
    The Department of Pathology, Tokushima University Hospital

Bibliographic Information

Other Title
  • イピリムマブ・ニボルマブ併用療法が著効した乳頭状腎細胞癌の1例
  • イピリムマブ ・ ニボルマブ ヘイヨウ リョウホウ ガ チョコウシタ ニュウトウジョウジンサイボウガン ノ 1レイ

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Abstract

We report a case of papillary renal cell carcinoma that responded well to the combination of ipilimumab and nivolumab. The patient was a 68-year-old male who was being followed up for a small left renal mass without treatment. Two years later, computed tomography (CT) showed enlarged cervical and para-aortic lymph nodes, and lymph node biopsy suggested metastases of the cancer. After resection of the renal tumor, we performed pararenal aortic lymph node biopsy, and we diagnosed the case as papillary renal cell carcinoma type 1 with lymph node metastasis. The combination of ipilimumab and nivolumab each metastatic site showed regression on CT. Since immune-related adverse events occurred during the therapy nivolumab was discontinued, but partial response of the metastases was maintained.

Journal

  • 泌尿器科紀要

    泌尿器科紀要 68 (4), 107-111, 2022-04-30

    泌尿器科紀要刊行会

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