High Resolution Structure Determination by Cryo-Electron Microscopy Single Particle Analysis
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- NAKANE Takanori
- Institute for Protein Research, Osaka University
Bibliographic Information
- Other Title
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- 低温電子顕微鏡単粒子解析法による高分解能構造解析
Abstract
<p>The past decade has seen revolutionary progress in single particle analysis with cryo-electron microscopes. Steady improvement in resolution has culminated in the reports of atomic resolution（1.2 Å）structures of apoferritin in 2020. This review, as a follow-up to my previous review in 2018, summarizes hardware and software improvements that enabled this milestone achievement. A quantitative analysis of the relationship between the number of particles and the resolution is presented and its practical implication in data collection strategies is discussed.</p>
Journal
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- Nihon Kessho Gakkaishi
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Nihon Kessho Gakkaishi 64 (2), 125-131, 2022-05-31
The Crystallographic Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390573726302288384
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- ISSN
- 18845576
- 03694585
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed