Two Cases of Resected Gastric Leiomyoma with Increased Accumulation on FDG-PET

  • Ogawa Yusuke
    Department of Gastroenterological Surgery, Toranomon Hospital
  • Ohkura Yu
    Department of Gastroenterological Surgery, Toranomon Hospital
  • Yago Akikazu
    Department of Gastroenterological Surgery, Toranomon Hospital
  • Shimoyama Hayato
    Department of Gastroenterological Surgery, Toranomon Hospital
  • Haruta Shusuke
    Department of Gastroenterological Surgery, Toranomon Hospital
  • Ueno Masaki
    Department of Gastroenterological Surgery, Toranomon Hospital

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Other Title
  • FDG-PETで集積亢進を示した胃平滑筋腫の2切除例

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Abstract

<p>Leiomyomas are benign tumors that are often negative on 18F-FDG-PET. Here, we report two relatively rare cases of gastric leiomyoma with increased FDG accumulation. In case 1, a 49-year-old man was admitted to our hospital for a submucosal tumor that showed strong FDG accumulation with a maximum standardized uptake value (SUVmax) of 8.17 from the esophagogastric junction to the gastric cardia. In case 2, a 27-year-old man visited our hospital because of an abnormal examination. A submucosal tumor with an ulcer was found in the gastric cardia. FDG-PET showed abnormal FDG accumulation with SUVmax 6.13. In both cases, laparoscopic proximal gastrectomy was performed based on the possibility of malignancy, and both tumors were diagnosed as gastric leiomyoma. The causes of increased FDG accumulation in leiomyoma may be increased blood flow in the tumor and overexpression of glucose transporter. A differential diagnosis is required because even benign leiomyoma may show false positives on FDG-PET. It is difficult to distinguish between benign and malignant myogenic submucosal tumors using a non-invasive method, and there is a need for establishment of appropriate examinations.</p>

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