Construction of the platform to explore drug target for IPF in Public/Private R&D Investment Strategic Expansion PrograM（PRISM）

DOI
  • Nakamura Yoshinori
    Artificial Intelligence Center for Health and Biomedical Research (ArCHER), National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)
  • Kitamura Hideya
    Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center
  • Ogura Takashi
    Kanagawa Cardiovascular and Respiratory Center
  • Natsume-Kitatani Yayoi
    Laboratory of Bioinformatics, Artificial Intelligence Center for Health and Biomedical Research (ArCHER), National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)
  • Mizuguchi Kenji
    Artificial Intelligence Center for Health and Biomedical Research (ArCHER), National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Institute for Protein Research, Osaka University

Bibliographic Information

Other Title
  • 官民研究開発投資拡大プログラム（PRISM）で構築する特発性肺線維症に対する創薬標的探索プラットフォームについて

Abstract

National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) and Kanagawa Cardiovascular and Respiratory Center have built an integrated multi-omics database that constitutes the world’s largest medical information repository for Idiopathic pulmonary fibrosis (Kanagawa Cohort Database) in Public/Private R&D Investment Strategic Expansion PrograM (PRISM). NIBIOHN have also developed AI for the data-driven exploration of drug targets by stratifying patients based on clinical and omics data (comprehensive biomolecular information). In addition to AI to explore drug targets, organizations participating in PRISM have also developed tools for the analysis of clinical text, automatic knowledge extraction, and automatic inference system. NIBOHN plan to launch an open platform to allow researchers both in industry and academia to widely use these systems in FY2022.

Journal

  • MEDCHEM NEWS

    MEDCHEM NEWS 32 (3), 119-123, 2022-08-01

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

  • CRID
    1390574411905871488
  • DOI
    10.14894/medchem.32.3_119
  • ISSN
    24328626
    24328618
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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