Optimized immunosuppression strategy in MHC-matched allogeneic iPS cell-based transplantation

Bibliographic Information

Other Title
  • MHC型一致他家iPS細胞由来組織移植に有効な免疫抑制剤併用プロトコールの構築

Description

<p>In transplantation medicine using iPS cells, it is planned to use off-the-shelf iPS cells derived from allogeneic iPS cells for rapid and low-cost utilization of clinical-grade cells. To reduce the possibility of rejection, it is designed to use HLA-homozygous iPS cells for the off-the-shelf product, and several lines have been established for future HLA-matched transplants. This article describes our efforts to control rejection in HLA-matched allogeneic iPS cell-based transplantation, focusing on establishing immunosuppression protocols.</p>

Journal

  • Organ Biology

    Organ Biology 29 (2), 133-137, 2022

    The Japan Society for Organ Preservation and Biology

Details 詳細情報について

  • CRID
    1390574490535796096
  • DOI
    10.11378/organbio.29.133
  • ISSN
    21880204
    13405152
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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