Optimized immunosuppression strategy in MHC-matched allogeneic iPS cell-based transplantation
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- Kamatani Tomoki
- Institute for Genetic Medicine, Hokkaido University
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- Seino Ken-ichiro
- Institute for Genetic Medicine, Hokkaido University
Bibliographic Information
- Other Title
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- MHC型一致他家iPS細胞由来組織移植に有効な免疫抑制剤併用プロトコールの構築
Description
<p>In transplantation medicine using iPS cells, it is planned to use off-the-shelf iPS cells derived from allogeneic iPS cells for rapid and low-cost utilization of clinical-grade cells. To reduce the possibility of rejection, it is designed to use HLA-homozygous iPS cells for the off-the-shelf product, and several lines have been established for future HLA-matched transplants. This article describes our efforts to control rejection in HLA-matched allogeneic iPS cell-based transplantation, focusing on establishing immunosuppression protocols.</p>
Journal
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- Organ Biology
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Organ Biology 29 (2), 133-137, 2022
The Japan Society for Organ Preservation and Biology
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Details 詳細情報について
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- CRID
- 1390574490535796096
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- ISSN
- 21880204
- 13405152
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed