Decrease in neutralizing antibody titers after SARS-CoV-2 vaccination in hemodialysis patients and the booster effect of a third vaccination
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- Ooyama Keiko
- Tsubasa Clinic, Medical Corporation Tsubasa
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- Kaneko Naoyuki
- Tsubasa Clinic, Medical Corporation Tsubasa
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- Kitazumi Yumiko
- Tsubasa Clinic, Medical Corporation Tsubasa
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- Yokozeki Mieko
- Tsubasa Clinic, Medical Corporation Tsubasa
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- Ooyama Hiroshi
- Ryougoku East Gate Clinic, Medical Corporation Tsubasa
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- Fujimori Shin
- Ryougoku East Gate Clinic, Medical Corporation Tsubasa
Bibliographic Information
- Other Title
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- 血液透析患者におけるSARS-CoV-2 ワクチン接種後の中和抗体価の低下と3 回目追加接種によるブースター効果
- ケツエキ トウセキ カンジャ ニ オケル SARS-CoV-2 ワクチン セッシュ ゴ ノ チュウワ コウタイカ ノ テイカ ト 3カイメ ツイカ セッシュ ニ ヨル ブースター コウカ
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Abstract
<p>We measured anti-SP-IgG antibody titers 6 months after the second dose of a SARS-CoV-2 vaccine (BNT162b2) and 1 month after the third vaccination in 105 hemodialysis patients, and examined the booster effect of the third vaccination. The mean anti-SP-IgG antibody titer at 6 months after the second vaccination was 499.2±619.4 AU/mL, which was about one-tenth lower than that seen 1 month after the second vaccination;however, 7 patients exhibited negative conversion (<50 AU/mL). The mean anti-SP-IgG antibody titer at 1 month after the third vaccination, including the cases involving negative conversion, had increased 85.7 times to 42,800.9±58,666.2 AU/mL, confirming the booster effect of the third vaccination. However, although the causes were unknown, there were two unresponsive cases.</p>
Journal
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- Nihon Toseki Igakkai Zasshi
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Nihon Toseki Igakkai Zasshi 55 (10), 589-593, 2022
The Japanese Society for Dialysis Therapy
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Details 詳細情報について
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- CRID
- 1390575373776928128
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- NII Book ID
- AN10432053
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- ISSN
- 1883082X
- 13403451
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- NDL BIB ID
- 032499270
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
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- Abstract License Flag
- Disallowed