Hyperthymia accompanied by electroencephalography aggravation in a pediatric patient treated with lacosamide

DOI
  • Fuse George
    Department of Pediatrics, Soka Municipal hospital, Soka, Saitama
  • Sugawara Yuji
    Department of Pediatrics, Soka Municipal hospital, Soka, Saitama
  • Hasegawa Takeshi
    Department of Pediatrics, Soka Municipal hospital, Soka, Saitama

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Other Title
  • Lacosamide投与中に気分高揚と脳波増悪を認めた1例

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Abstract

<p>  A 6-year-old girl collapsed and experienced seizures. Her seizures were successfully suppressed with the use of lacosamide (LCM). However, she had a hyperthymic temperament sometimes, such as laughing excessively at trivial matters. The generalized spike and wave complexes seen before LCM administration were extremely aggravated, and slow waves appeared in background activity on electroencephalography (EEG). When we changed from LCM to Valproic acid, the psychiatric symptoms immediately disappeared and the EEG improved. Therefore, when psychiatric symptoms are seen after LCM administration, EEG is strongly recommended.</p>

Journal

  • NO TO HATTATSU

    NO TO HATTATSU 54 (6), 448-450, 2022

    The Japanese Society of Child Neurology

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