Evacuation of tissue and blood biomarkers of progression to NASH cirrhosis by six liver biopsies: a case report

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  • KAWADA Mayuko
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • KAWANAKA Miwa
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • ISHII Katsunori
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • KATSUMATA Ryo
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • TANIKAWA Tomohiro
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • URATA Noriyo
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • NISHINO Ken
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • SUEHIRO Mitsuhiko
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • HARUMA Ken
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School
  • KAWAMOTO Hirofumi
    Department of General Internal Medicine 2, Kawasaki Medical Center, Kawasaki Medical School

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Other Title
  • 6回の肝生検によりNASH肝硬変への進展を血液検査と肝組織像で対比できた1例

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<p>We present a 56-year-old female patient diagnosed with stage 2/grade 3 non-alcoholic steatohepatitis (NASH) via liver biopsy. Over the next 14 years, six liver biopsies were performed, and the patient was followed up clinically. This was a valuable case wherein we were able to investigate the histology of the liver and the timing of changes in the AST/ALT ratio, platelets, albumin, FIB4-Index, and liver fibrosis markers.</p>

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