A new approach to pancreatic neuroendocrine tumors using tissue clearing technology with three-dimensional imaging

DOI Web Site 19 References
  • IKEDA Eriko
    Department of Internal Medicine, Division of Pathology, Jichi Medical University Department of Internal Medicine, Division of Gastroenterology, Jichi Medical University
  • FUKUSHIMA Noriyoshi
    Department of Internal Medicine, Division of Pathology, Jichi Medical University

Bibliographic Information

Other Title
  • 組織透明化技術と3Dイメージングによる膵神経内分泌腫瘍へのアプローチ

Abstract

<p>Conventional histopathological evaluation can only view arbitrary cross sections of a histologic specimen. However, recently, it is possible to observe the entire specimen using tissue clearing technology with three-dimensional imaging. If the entire specimen can be evaluated, the three-dimensional structure of the tissue is observed. As a result, there are benefits such as fewer missed lesions and the clarification of new pathologic entities. There are dozens of tissue clearing reagents available. Each reagent and microscope has its own characteristics. It is important to select the appropriate reagent and microscope according to the intended purpose. Tissue clearing technology is reviewed in this paper. The evaluation of Pancreatic Neuroendocrine Neoplasms by tissue clearing technology with three-dimensional imaging is introduced.</p>

Journal

  • Suizo

    Suizo 38 (1), 44-50, 2023-02-28

    Japan Pancreas Society

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