Cancer of the ampulla of vater in lynch syndrome : a case report
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- Kanke Yasuyuki
- Department of Surgery, Hoshi General Hospital
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- Ito Taisuke
- Department of Surgery, Hoshi General Hospital
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- Sugawara Ryota
- Department of Surgery, Hoshi General Hospital
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- Tojo Kako
- Department of Surgery, Hoshi General Hospital
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- Fujita Shotaro
- Department of Surgery, Hoshi General Hospital
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- Yashima Rei
- Department of Surgery, Hoshi General Hospital
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- Katsube Yosuke
- Department of Genetic Counseling, Hoshi General Hospital
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- Tabata Kenichi
- Department of Diagnostic Pathology, Hoshi General Hospital
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- Nomizu Tadashi
- Department of Surgery, Hoshi General Hospital Department of Genetic Counseling, Hoshi General Hospital
Bibliographic Information
- Other Title
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- Vater 乳頭部癌を合併したLynch 症候群の1 例
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Abstract
<p>Abstract : A 56-years-old male presented at our hospital due to the symptoms of anemia, liver disfunction and colon polyps. He had resected rectal cancer at the ages of 41 and has no family history of colorectal cancer. A thorough examination for anemia resulted in detection of multiple colon cancer and cancer on ampulla of Vater. We performed total colectomy with dissection of regional lymph nodes and pancreaticoduodenectomy with dissection of regional lymph nodes. Immunohistochemical analysis showed a lack of MSH2 and MSH6 protein in the colon cancer and cancer on ampulla of Vater, and germline mutation of hMSH2 gene was recognized. Therefore, we diagnosed the case as Lynch syndrome.</p>
Journal
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- FUKUSHIMA MEDICAL JOURNAL
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FUKUSHIMA MEDICAL JOURNAL 73 (1), 13-18, 2023
Fukushima Society of Medical Science
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Details 詳細情報について
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- CRID
- 1390577154752610944
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- NII Book ID
- AN00216776
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- ISSN
- 24367826
- 00162582
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- Crossref
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- Abstract License Flag
- Allowed