Gestational Weight Gain Growth Charts Adapted to Japanese Pregnancies Using a Bayesian Approach in a Longitudinal Study: The Japan Environment and Children’s Study

  • Morisaki Naho
    Department of Social Medicine, National Research Institute for Child Health and Development
  • Piedvache Aurélie
    Department of Social Medicine, National Research Institute for Child Health and Development
  • Morokuma Seiichi
    Department of Health Science, Graduate School of Medical Science, Kyushu University Research Center for Environmental and Developmental Medical Sciences, Kyushu University
  • Nakahara Kazushige
    Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University
  • Ogawa Masanobu
    Research Center for Environmental and Developmental Medical Sciences, Kyushu University
  • Kato Kiyoko
    Research Center for Environmental and Developmental Medical Sciences, Kyushu University Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University
  • Sanefuji Masafumi
    Research Center for Environmental and Developmental Medical Sciences, Kyushu University Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University
  • Shibata Eiji
    Japan Environment and Children’s Study, UOEH Subunit Center, University of Occupational and Environmental Health Department of Obstetrics and Gynecology, School of Medicine, University of Occupational and Environmental Health
  • Tsuji Mayumi
    Japan Environment and Children’s Study, UOEH Subunit Center, University of Occupational and Environmental Health Department of Environmental Health, School of Medicine, University of Occupational and Environmental Health
  • Shimono Masayuki
    Japan Environment and Children’s Study, UOEH Subunit Center, University of Occupational and Environmental Health Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health
  • Kawamoto Toshihiro
    Japan Environment and Children’s Study, UOEH Subunit Center, University of Occupational and Environmental Health
  • Ohga Shouichi
    Research Center for Environmental and Developmental Medical Sciences, Kyushu University Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University
  • Kusuhara Koichi
    Japan Environment and Children’s Study, UOEH Subunit Center, University of Occupational and Environmental Health Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health

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<p>Background: Tracking gestational weight gain (GWG) during pregnancy makes it possible to optimize pregnancy outcomes, and GWG growth curves are well suitable for this purpose. The GWG guidelines for Japanese were revised in 2021. However, currently, there are no GWG growth curves to guide women on how to gain weight to meet these guidelines.</p><p>Methods: Using data on 96,631 live births from the Japan Environment and Children’s Study (JECS), we created descriptive GWG percentile curves estimating the trajectory of GWG required to meet the GWG guidelines stratified by pre-pregnancy body mass index (BMI). For both analyses, Bayesian mixed models with restricted cubic splines adjusted for maternal characteristics were used.</p><p>Results: GWG curves substantially differed by pre-pregnancy BMI and were higher among multiparas and those with lower maternal age and with no previous disease. We estimated that underweight, normal weight, overweight, and obese women who gain 8.4 to 11.1 kg, 6.4 to 9.1 kg, 3.8 to 6.5 kg, and <1.9 kg at 30 weeks of gestation are on the trajectory to reach the new guidelines at 40 weeks of gestation.</p><p>Conclusion: We provide GWG percentiles curves for Japanese women, as well as GWG trajectory curves to meet the new GWG recommendations. These results may help pregnant women monitor weight during pregnancy.</p>

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