Torpor research toward the synthetic hibernation

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  • 人工冬眠の実現にむけた休眠研究の取り組み
  • ジンコウ トウミン ノ ジツゲン ニ ムケタ キュウミン ケンキュウ ノ トリクミ

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Abstract

Some mammals actively reduce energy demand by minimalizing their vital biological functions when facing winter or starvation. This is called torpor, divided into either daily torpor (minutes to hours in length) or hibernation (days to weeks). The surprising features of hibernation are not only hypometabolism and low body temperature but their biological function remaining intact after recovering from torpor. Implementing such hypometabolic and low body temperature resistance in humans as synthetic hibernation is expected to become a new treatment for diseases with insufficient energy supply, such as respiratory and circulatory failure.

Journal

  • 低温科学

    低温科学 81 141-147, 2023-03-20

    低温科学第81巻編集委員会

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