Indolent T-cell lymphoma with pleural effusion and neurological signs in a cat: A case report.
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- Hori Hideya
- Tsujido Cats & Dogs Hospital
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- Narita Tsuyoshi
- Tsujido Cats & Dogs Hospital
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- Higuchi Go
- Tsujido Cats & Dogs Hospital
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- Mori Takuro
- Tsujido Cats & Dogs Hospital
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- Kono Shota
- Tsujido Cats & Dogs Hospital
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- Nomoto Ken
- Tsujido Cats & Dogs Hospital
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- Nina Takahito
- Tsujido Cats & Dogs Hospital
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- Shiroshita Yukihito
- Clinic for Veterinary Respiratory Medicine and Surgery
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- Inaba Kenichi
- Clinic for Veterinary Respiratory Medicine and Surgery
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- Noda Takahiro
- Yasuda Animal Hospital
Bibliographic Information
- Other Title
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- 胸水および中枢神経徴候を呈した猫の緩徐進行型T細胞性リンパ腫の1例
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Abstract
<p>This case report describes a 10-year-old castrated male Russian Blue cat who was referred to the hospital for respiratory distress and coughing. Tests for FeLV and FIV infection were negative. Pleural fluid was removed and subjected to cytological and lymphocyte clonality analysis. Thoracic radiography and ultrasonography confirmed atelectasis in some pulmonary lobes. The cat was diagnosed with stage III small- to medium-cell T cell lymphoma, and was treated with prednisolone (5 mg/head) and L-asparaginase (10000 units/m2). With this treatment, the pleural effusion gradually subsided and respiratory signs improved. However, the cat developed decreased motor function of the hindlimbs, forelimbs, and tongue, leading to the administration of 1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) (10mg/head or 38 mg/m2) for suspected central nervous system infiltration of lymphoma. Neurological signs dramatically improved within seven days, and CCNU (15mg/head or 54 mg/m2) was administered five more times until day 284, after which it was replaced with chlorambucil (2mg/head every four days). On day 393, weight loss and abdominal lymphadenopathy were observed, and CCNU (10mg/head) was administered again on the day 407 but was ineffective. Unfortunately, the cat eventually died on the day 466 with marked abdominal lymphadenopathy.</p>
Journal
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- Journal of Japan Veterinary Cancer Society
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Journal of Japan Veterinary Cancer Society 12 (1), 7-12, 2023-05-31
Japan Veterinary Cancer Society
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Keywords
Details 詳細情報について
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- CRID
- 1390577696510456320
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- ISSN
- 18843352
- 18843344
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed