The Usefulness of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for AL Amyloidosis Presenting as Mediastinal Lymphadenopathy: a Case Report

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  • Ito Toshiyuki
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine
  • Yoshida Masamichi
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Miki Hiroto
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Goto Hiroki
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Kodama Shuji
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Terashima Toshikazu
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Fujiwara Atsushi
    Department of Pulmonary Medicine, Mie Prefectural General Medical Center
  • Tomaru Atsushi
    Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine
  • Fujimoto Hajime
    Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine
  • Kobayashi Tetsu
    Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine

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Other Title
  • 縦隔リンパ節病変に対するEBUS-TBNAが診断に有用であったALアミロイドーシスの1例

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<p>Background. The usefulness of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for diagnosing hilar and mediastinal lymph node lesions is well-recognized. However, there have been few reports concerning the usefulness of EBUS-TBNA for diagnosing amyloidosis presenting as hilar and mediastinal lymphadenopathy. Case. A 77-year-old woman was referred to us for a hilar and mediastinal lymphadenopathy assessment after receiving treatment for colorectal cancer and lung cancer. We found deposits of amyloid in mediastinal lymph node lesions on EBUS-TBNA and made a final diagnosis of AL amyloidosis. Conclusion. EBUS-TBNA is a minimally invasive test and useful for diagnosing amyloidosis presenting as mediastinal lymphadenopathy because a sufficient tissue sample can be obtained. It should thus be considered as a diagnostic tool option.</p>

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