オトガイ形成術に使用したポリ-L-乳酸プレートによる遅発性異物反応をみとめた1例

  • 伊藤 篤志
    洛和会音羽病院京都口腔健康センター口腔外科
  • 森 宏樹
    洛和会音羽病院京都口腔健康センター口腔外科 洛和会音羽病院京都顎変形症センター
  • 宮本 絵里加
    洛和会音羽病院京都口腔健康センター口腔外科
  • 今井 裕一郎
    洛和会音羽病院京都口腔健康センター口腔外科 奈良県立医科大学口腔外科学講座
  • 横江 義彦
    洛和会音羽病院京都顎変形症センター
  • 桐田 忠昭
    奈良県立医科大学口腔外科学講座

書誌事項

タイトル別名
  • A Case of Delayed-onset Foreign Body Reaction Caused by Bioabsorbable Poly-L-lactic Acid Plates after Genioplasty
  • オトガイ ケイセイジュツ ニ シヨウ シタ ポリ-L-ニュウサン プレート ニ ヨル チハツセイ イブツ ハンノウ オ ミトメタ 1レイ

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抄録

Recently, bioabsorbable osteosynthesis materials have been improved and their use is increasing for orthognathic surgery and maxillofacial fracture because secondary operation is not necessary. However, some adverse effects have been reported, such as wound infection, failure of fixation and late-onset reaction. <br>We report a case of delayed-onset foreign body reaction caused by bioabsorbable plates. A 23-year-old female was referred to our department because of mandibular retrognathism. One year after maxillo-mandibular osteotomy, removal of titanium plates and genioplasty were carried out with hydroxyapatite/poly-L-lactic acid plates. Two years and 9 months after genioplasty, she re-consulted our department with pain and swelling of the chin. <br>A lateral cephalogram was taken at re-consultation, and showed that the chin bone fragment was stable compared with that at 6 months after genioplasty. However, dental cone beam computed tomography suggested loosening of bioabsorbable screws and plates. <br>There was no discharge of pus from the area of late-onset inflammatory reaction, and specific pathogens were not detected by culture analysis. We removed fragments of bioabsorbable osteosynthesis materials and granulation tissues under general anesthesia. Histopathological diagnosis was foreign granulomas. Thus, we diagnosed this case as a late-onset foreign body inflammatory reaction to hydroxyapatite/poly-L-lactic acid plates.

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