A clinical investigation of local recurrence of hypopharyngeal squamous cell carcinoma after definitive radiation therapy

DOI Web Site 18 References
  • Ono Takeharu
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Chitose Shun-Ichi
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Sueyoshi Shintaro
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Kurita Takashi
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Fukahori Mioko
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Sato Fumihiko
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Sato Kiminobu
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine
  • Umeno Hirohito
    Department of Otolaryngology–Head and Neck Surgery, Kurume University School of Medicine

Bibliographic Information

Other Title
  • 下咽頭扁平上皮癌放射線治療後の局所再発に対する救済手術の検討

Search this article

Abstract

This study investigated patients with local recurrence of hypopharyngeal squamous cell carcinoma after definitive radiation therapy. Of 222 patients treated with （chemo） radiation therapy, local recurrence was observed in 49 patients, 18 of whom underwent salvage surgery. Salvage surgery included 4 patients who underwent transoral surgery and 14 who underwent total or partial pharyngectomy with total laryngectomy. The median timeframe for detecting local recurrence after completing the initial treatment was 6.3 months, and 38 of 49 patients with local recurrence were detected within 12 months. Additionally, the 5-year local control, overall survival, and disease-free survival rates of patients who underwent salvage surgery were 59.6％, 44.4％, and 38.9％, respectively. Regional recurrence, positive surgical margin, including close to margin, and pathological T4a are the worst prognostic factors. Therefore, detecting local recurrence at a low T stage and negative surgical margin in salvage surgery are considered important.

Journal

References(18)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top