両側性ラヌーラを契機として診断に至った小児シェーグレン症候群の1例

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  • A case of childhood Sjögren’s syndrome diagnosed due to bilateral plunging ranula
  • リョウソクセイ ラヌーラ オ ケイキ ト シテ シンダン ニ イタッタ ショウニ シェーグレン ショウコウグン ノ 1レイ

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<p>We report a case of childhood Sjögren’s syndrome (CSS) in a 13-year-old girl, diagnosed due to bilateral plunging ranula. Sjögren’s syndrome (SS) is an autoimmune disease in which various autoantibodies appear, mainly in sialadenitis and dacryoadenitis. Plunging ranula is a salivary gland disease often encountered in daily clinical work. It is considered to be one of the clinical symptoms of SS, but this is not widely known. MRI scans showed fluid retention in the bottom of the mouth on both sides, suggesting bilateral plunging ranula. Laboratory examination showed positivity for anti-Ro/SS-A antibody, anti-La/SS-B antibody, immunoglobulin G (IgG), rheumatoid factor (RF) and antinuclear antibody, indicating CSS. Fenestration of the plunging ranula and a lip biopsy were performed, and histopathological examination of the minor salivary gland revealed chronic inflammation; hence, a diagnosis of CSS was made. Examination in the rheumatology department showed no extraglandular symptoms, and the treatment policy was to conduct follow up. A favorable outcome was achieved, with no evidence of recurrence two years postoperatively.</p>

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