A Case of Germ Cell Tumor in which Necrotic Tissue Revealed hCG-Positive in Surgical Specimen of Post-Chemotherapy Retroperitoneal Lymph Node Dissection

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  • SAKURAI Hiromichi
    The Department of Urology, International University of Health and Welfare Narita Hospital
  • KAWAI Koji
    The Department of Urology, International University of Health and Welfare Narita Hospital
  • ONOZAWA Mizuki
    The Department of Urology, International University of Health and Welfare Narita Hospital
  • INOUE Takamitsu
    The Department of Urology, International University of Health and Welfare Narita Hospital
  • MIYAZAKI Jun
    The Department of Urology, International University of Health and Welfare Narita Hospital

Bibliographic Information

Other Title
  • 化学療法後の後腹膜リンパ節郭清で壊死組織がhCG陽性であった胚細胞腫瘍の1例
  • カガク リョウホウ ゴ ノ アトバラマク リンパセツカクセイ デ エシ ソシキ ガ hCG ヨウセイ デ アッタ ハイサイボウ シュヨウ ノ 1レイ

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Description

The patient was a 27-year-old male. In December 2020, he was diagnosed with a primary extragonadal germ cell tumor of the retroperitoneum with inferior vena caval (IVC) involvement. After 3 courses of bleomycin, etoposide and cisplatinum and 3 courses of paclitaxel, ifosfamide and cisplatin, the serum human chorionic gonadotropin (hCG) level remained abnormally low. He was referred to our department after follow-up for 2 months. Since the hCG level continued to decrease during follow-up, we decided to perform marker-positive surgery. He underwent retroperitoneal lymph node dissection. We also resected a part of the IVC wall and tumor in the IVC. The serum hCG level was normalized at 5 days after surgery. Pathological examination revealed only necrotic tissue. Immunohistochemistry showed hCG positive in the necrotic tissue.

Journal

  • 泌尿器科紀要

    泌尿器科紀要 69 (6), 157-162, 2023-06-30

    泌尿器科紀要刊行会

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