Neurosurgical perioperative management of frail elderly patients

  • Hu Xiqi
    Department of Neurosurgery, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine Haikou, China. Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Ma Yanan
    Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan. Department of Gastroenterology, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
  • Jiang Xuemei
    Department of Gastroenterology, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
  • Tang Wei
    International Health Care Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Xia Ying
    Department of Neurosurgery, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine Haikou, China.
  • Song Peipei
    Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.

説明

<p>With the rapid increase in global aging, the prevalence of frailty is increasing and frailty has emerged as an emerging public health burden. Frail elderly patients suffer from reduced homeostatic reserve capacity, which is associated with a disproportionate decline in physical status after exposure to stress and an increased risk of adverse events. Frailty is closely associated with changes in the volume of the white and gray matter of the brain. Sarcopenia has been suggested to be an important component of frailty, and reductions in muscle strength and muscle mass lead to reductions in physical function and independence, which are critical factors contributing to poor prognosis. Approximately 10–32% of patients undergoing neurological surgery are frail, and the risk of frailty increases with age, which is significantly associated with the occurrence of adverse postoperative events (major complications, total duration of hospitalization, and need for discharge to a nursing facility). The postoperative mortality rate in severely frail patients is 9–11 times higher than that in non-frail individuals. Therefore, due attention must be paid to neurosurgical frailty and muscle assessment in elderly patients. Specialized interventions in the perioperative period of neurosurgery in frail elderly patients may improve their postoperative prognosis. </p>

収録刊行物

  • BioScience Trends

    BioScience Trends 17 (4), 271-282, 2023-08-31

    特定非営利活動法人 バイオ&ソーシャル・サイエンス推進国際研究交流会

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