Advanced Appendiceal Cancer with Systematic Metastasis without Gastrointestinal Symptoms Found by Subcutaneous Tumor
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- Nakamura Satoshi
- Department of Gastroenterology, Toranomon Hospital, Japan
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- Ochiai Yorinari
- Department of Gastroenterology, Toranomon Hospital, Japan
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- Nishihara Yuki
- Department of Gastroenterological Surgery, Toranomon Hospital, Japan
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- Koyanagi Anri
- Department of Pathology, Toranomon Hospital, Japan
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- Miura Yasurou
- Department of Pathology, Toranomon Hospital, Japan
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- Kikuchi Daisuke
- Department of Gastroenterology, Toranomon Hospital, Japan
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- Takazawa Yutaka
- Department of Pathology, Toranomon Hospital, Japan
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- Kuroyanagi Hiroya
- Department of Gastroenterological Surgery, Toranomon Hospital, Japan
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- Hoteya Shu
- Department of Gastroenterology, Toranomon Hospital, Japan
Abstract
<p>An 86-year-old woman with a subcutaneous nodule in her left axilla visited our hospital. She had no gastrointestinal symptoms, but contrast-enhanced computed tomography revealed a cecal mass and systemic metastasis, including cutaneous, bone, peritoneal dissemination and ascites. Colonoscopy revealed a circumferential, elevated cecal lesion. She underwent right hemicolectomy to prevent colon obstruction. The pathological diagnosis was poorly differentiated adenocarcinoma (por1>tub2>muc) arising from the appendix with a BRAFV600E mutation and microsatellite instability-high. Chemotherapy was administered, and she is currently still alive and undergoing chemotherapy. We describe a rare case of advanced appendiceal cancer without gastrointestinal symptoms diagnosed due to cutaneous metastasis. </p>
Journal
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- Internal Medicine
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Internal Medicine 62 (18), 2655-2660, 2023-09-15
The Japanese Society of Internal Medicine