Tau imaging in chronic stage of single moderate to severe traumatic brain injury

DOI
  • Ueno Senkei
    Department of Psychiatry, Kyoto University Graduate School of Medicine

Bibliographic Information

Other Title
  • 中等症から重症の単発外傷性脳損傷の慢性期におけるタウイメージング

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Description

Repetitive head trauma can induce chronic traumatic encephalopathy (CTE) . CTE is defined as tauopathy because of neuropathologic findings indicative of tau deposition, such as neurofibrillary tangles. Single moderate to severe traumatic brain injury can also produce CTE-like psychiatric and neurological symptoms and neuropathological changes in the chronic phase. Tau imaging in the chronic phase of single moderate to severe single traumatic brain injury shows focal accumulation of tau tracer at the depths of cerebral sulci in some cases. Neuroinflammation can be one of the factors involved in tau pathology in traumatic brain injury. In selecting reference tissues for tau imaging, it is important to consider that the cerebellum is an area where tau can accumulate in CTE.

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Details 詳細情報について

  • CRID
    1390579057079450752
  • DOI
    10.11249/jsbpjjpp.34.3_117
  • ISSN
    21866465
    21866619
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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