Development and Evaluation of a New Clinical Trial Information Retrieval/provision System Based on Comprehensive Cancer Genomic Profiling Tests

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  • Itamura Ryo
    Department of Pharmaceutical Services, Hiroshima University Hospital
  • Motonaga Masanori
    Department of Pharmaceutical Services, Hiroshima University Hospital
  • Okamoto Wataru
    Cancer Treatment Center, Hiroshima University Hospital
  • Teratani Yusuke
    Department of Pharmaceutical Services, Hiroshima University Hospital
  • Saeki Yasuyuki
    Department of Pharmaceutical Services, Hiroshima University Hospital
  • Matsuo Hiroaki
    Department of Pharmaceutical Services, Hiroshima University Hospital
  • Hinoi Takao
    Department of Clinical and Molecular Genetics, Hiroshima University Hospital

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  • がん遺伝子パネル検査結果に基づく臨床試験情報検索・提供システムの新規構築

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Abstract

<p>Cancer genome medicine is personalized medicine based on genetic information through cancer gene panel testing, in which cancer tissue and blood are analyzed by next-generation sequencers. Pharmacists participate in the expert committee in cancer gene medicine at Hiroshima University Hospital and provide clinical trial information based on the genetic mutation of each case. We have established a new database (Hirodai-DB) to improve the efficiency of providing clinical trial information and to increase the amount of clinical trial information provided. Six out of 123 cases actually proceeded to clinical trials using Hirodai-DB, and 2 out of 6 cases (33％) that proceeded to clinical trials used Hirodai-DB that was the only source of information. The establishment of the Hirodai-DB was considered to be useful for cancer genome medicine at this hospital.</p>

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