An anatomical case of obstructive jaundice due to the rapid enlargement of hepatic peribiliary cysts in end-stage alcoholic liver cirrhosis

  • YOSHIMURA Chisato
    Department of Gastroenterology, Higashiosaka City Medical Center
  • MURATA Jun
    Department of Gastroenterology, Higashiosaka City Medical Center Department of Gastroenterology, Ikeda City Hospital
  • YAMAUCHI Amane
    Department of Pathology, Higashiosaka City Medical Center
  • SUNAGA Koji
    Department of Gastroenterology, Higashiosaka City Medical Center
  • KATO Mina
    Department of Gastroenterology, Higashiosaka City Medical Center
  • TAKIGAWA Atsuo
    Department of Gastroenterology, Higashiosaka City Medical Center
  • NAWA Takatoshi
    Department of Gastroenterology, Higashiosaka City Medical Center
  • AKAMATSU Haruki
    Department of Gastroenterology, Higashiosaka City Medical Center
  • KOBAYASHI Ichizo
    Department of Gastroenterology, Higashiosaka City Medical Center
  • TSUJII Masahiko
    Department of Gastroenterology, Higashiosaka City Medical Center

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Other Title
  • アルコール性肝硬変の末期に胆管周囲囊胞が急増大し閉塞性黄疸を認めた1剖検例

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Abstract

<p>A man in his 60s had end-stage alcoholic cirrhosis. About six months before his death, hepatic peribiliary cysts (HPBC) rapidly increased, and he developed jaundice and liver failure. The pathological autopsy performed after his death revealed that his intrahepatic bile duct was pressured due to multiple cysts caused by HPBC, which resulted in liver failure. Some cases of HPBC have been associated with alcoholic cirrhosis;however, no other cases of increased HPBC in a short period of time have been reported. Although identifying the cause of increased HPBC in a short time is difficult in this case, it may be have been caused by continuous alcohol drinking after the onset of HPBC. Most patients with HPBC have liver cirrhosis and obstructive jaundice that may promote liver failure as in this case. Therefore, patients with HPBC should not only be instructed for abstinence but also promptly consider effective treatments in the event of obstructive jaundice to prevent liver dysfunction.</p>

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