Effects of Mosquito-Imitated Microneedle's Reciprocating Rotations on Puncture Resistance Forces : Evaluations by Puncturing Experiments and Nonlinear FEM Analyses
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- Mizutsu Akira
- Kansai University
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- Okumura Yuki
- Panasonic Holdings Corporation
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- Ueda Atsushi
- Panasonic Holdings Corporation
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- Yamamoto Shunki
- Kansai University
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- Takahashi Tomokazu
- Kansai University
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- Suzuki Masato
- Kansai University
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- Aoyagi Seiji
- Kansai University
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- Nagashima Toshio
- Sophia University
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- Chiyonobu Makoto
- JSOL Corporation
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- Nishikawa Hideki
- FUTA-Q, Ltd.
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- Sudo Fumio
- FUTA-Q, Ltd.
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- Ohdaira Toshiyuki
- Yamada Seiko Co., Ltd.
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- Seshimo Satoshi
- Yamada Seiko Co., Ltd.
書誌事項
- タイトル別名
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- Effects of Mosquito-Imitated Microneedle’s Reciprocating Rotations on Puncture Resistance Forces—Evaluations by Puncturing Experiments and Nonlinear FEM Analyses—
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抄録
<p>Development of a low-invasive microneedle is currently desired in the medical field to mitigate the patients’ stress and pain. We have paid attention to mosquitoes that puncture the skin without giving humans no feelings of pain. We have observed mosquitoes and found that when their proboscis punctures human skin, they make the following three behaviors: apply tension to human skin; rotate their proboscis; vibrate their proboscis. In our previous studies, we developed a bundled set of three microneedle imitating the mosquito’s proboscis and experimentally proved the usefulness of their alternate vibrations, which is one of the mosquito’s puncturing behaviors. However, the setting of three needles with proper clearances from each other was difficult, making their driving system too complex to practically use it. Therefore, we have developed a simplified microneedle by reducing the number of needles from three to two or one. This paper has focused on the effects of the rotations of a single needle. Using our developed microneedle with a diameter of 90 µm and the thinnest commercial microneedle with a diameter of 180 µm, we evaluated the effect of reciprocating rotation, one of the mosquitoes’ puncturing behaviors, by puncture experiments using artificial skin and nonlinear finite element method (FEM) analysis. As a result, it was found that the reciprocating rotation suppresses the puncture resistance force and the skin deflection.</p>
収録刊行物
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- International Journal of Automation Technology
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International Journal of Automation Technology 18 (2), 276-286, 2024-03-05
富士技術出版株式会社