A case of local recurrent pancreatic neuroendocrine tumor, grade 3, after a laparoscopic distal pancreatectomy, showing the intraductal extension, exposure, and through the papilla of Vater access

DOI Web Site 9 References
  • KATO Hiroyuki
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • ASANO Yukio
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • ITO Masahiro
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • ARAKAWA Satoshi
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • SHIMURA Masahiro
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • KOIKE Daisuke
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • OCHI Takayuki
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • KAWAI Toki
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • YASUOKA Hironobu
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • HIGASHIGUCHI Takahiko
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • KUNIMURA Yoshiki
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • TANI Hiroki
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • HORIGUCHI Kazuma
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • NAGATA Hidetoshi
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • KONDO Yuka
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • SATO Harunobu
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • KATO Yutaro
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • HANAI Tsunekazu
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • HORIGUCHI Akihiko
    Department of Gastroenterological Surgery, Fujita Health University School of Medicine, Bantane Hospital
  • URANO Makoto
    Department of Diagnostic Pathology, Fujita Health University School of Medicine, Bantane Hospital

Bibliographic Information

Other Title
  • 腹腔鏡下膵体尾部切除後に局所再発し，主膵管内進展，Vater乳頭からの腫瘍脱出を認めた膵神経内分泌腫瘍G3の一例

Abstract

<p>Case: The patient was a 55-year-old female. A tumor of the pancreatic tail was found during a medical examination, and a laparoscopic distal pancreatectomy was performed at our hospital. Histological examination revealed the diagnosis of a pancreatic neuroendocrine tumor (PanNET) grade 3 (G3) (Ki-67 index: 20-30%). Seven months after the initial surgery, bile duct dilatation and abnormal liver functions〔aspartate aminotransferase (AST): 171U/l, alanine transaminase ALT: 86U/l〕were observed, and upper gastrointestinal endoscopy was performed for further examination, showing a papillary reddish tumor with a white coat protruding from the papilla of Vater. Considering the possibility of local recurrence of PanNET G3, although not typical, the patient underwent a remnant total pancreatectomy. Histologically, immunohistochemical stains were positive for synaptophysin and chromogranin A, and the Ki-67 index was around 30-40%, indicating that this tumor was a recurrence of the PanNET G3. The patient is alive without any recurrence at 24 months after the second surgery.</p>

Journal

  • Suizo

    Suizo 39 (1), 72-78, 2024-02-29

    Japan Pancreas Society

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