Protein Structure Prediction to Function Prediction Using AlphaFold

DOI Web Site 33 References
  • TOMII Kentaro
    Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST)

Bibliographic Information

Other Title
  • AlphaFoldによる蛋白質立体構造予測から機能予測へ

Description

<p>AlphaFold which builds in deep learning-based methods based on large amounts of protein data allows us highly accurate structure prediction/modeling for most proteins. AlphaFold models of proteins can be useful for diverse applications such as predictions of intrinsically disordered regions, modeling of structures based on cryo-EM maps and ligand binding site predictions. Here, we introduce and review the backgrounds, effects and caveats of protein structure/complex structure prediction using AlphaFold/AlphaFold-Multimer.</p>

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 64 (1), 5-11, 2024

    The Biophysical Society of Japan General Incorporated Association

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