Efficacy of totarol against <i>Staphylococcus pseudintermedius</i> and <i>Staphylococcus coagulans</i> in dogs and cats

DOI

Bibliographic Information

Other Title
  • An <i>in vitro</i> study

Description

We investigated the susceptibility of totarol in 20 staphylococci strains, consisting of Staphylococcus pseudintermedius (n = 10) and S. coagulans (n = 10), from dogs and cats with skin infections. Each species contained 5 methicillin-resistant and 5 methicillin-susceptible strains. The minimum inhibitory concentrations (MICs) of totarol were determined by microbroth dilution method. As a result, all strains had the MIC of 4 μg/mL, except for one methicillin-susceptible S. coagulans strain, which had the MIC of 40 μg/mL. These MICs were extremely lower than the totarol concentration in commercially-available topical products. The present findings would support the use of totarol-containing topical products as one of the treatment options for canine and feline skin infections with both methicillin-susceptible and -resistant staphylococci.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390581148791629824
  • DOI
    10.57494/jjvr.71.4_117
  • ISSN
    2758447X
    00471917
  • Text Lang
    en
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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