A Case of Pneumatosis Cystoides Intestinalis Caused by α-glucosidase Inhibitor Treatment

DOI Web Site

Bibliographic Information

Other Title
  • α-グルコシダーゼ阻害薬の関与が疑われた腸管囊腫様気腫症の1例
  • a-グルコシダーゼ ソガイヤク ノ カンヨ ガ ウタガワレタ チョウカンノウ シュ ヨウキシュショウ ノ 1レイ

Search this article

Abstract

<p>A 77-year-old man with a 10-days’ history of abdominal pain and distension was referred to our hospital. Abdominal contrast-enhanced CT revealed massive intestinal emphysema and intraabdominal free air. The patient gave a 6-month history of receiving α-glucosidase inhibitor (α-GI) treatment and of suffering from constipation and abdominal distension during this period. Laparoscopic exploration revealed pneumatosis cystoides intestinalis (PCI), but no evidence of intestinal perforation. We reviewed the data of 32 cases reported in Japan and found that such cases probably require no surgery, including laparoscopic exploration, that a good prognosis can be achieved with conservative treatment, and that there have been no fatalities associated with this condition. Therefore, the possibility should be borne in mind of the development of PCI during α-GI treatment and drugs of this class should be administered with caution.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top