Successful management of isolated bile leakage from the caudate lobe following pancreaticoduodenectomy through the administration of minocycline hydrochloride injection: A case report

DOI

Bibliographic Information

Other Title
  • 塩酸ミノサイクリン注入が有効であった膵頭十二指腸切除術後のSpiegel葉からの離断型胆汁漏の1例

Abstract

<p>A 72-year-old female underwent subtotal stomach-preserving pancreaticoduodenectomy for pancreatic head cancer. On the 16th post operative day, fistulography of the drain placed at the pancreaticogastric anastomosis revealed isolated bile leakage from the bile duct of the Spiegel lobe. Drainage was continued, and a 5 Fr balloon catheter was employed to inject 10mg of minocycline on the 27th postoperative day, followed by additional injections of 30mg on the 30th, 33rd, and 36th days postoperative day. No significant adverse effects were observed. Consequently, the bile leakage was relieved and the amount of drainage was reduced, ultimately leading to the removal of the drain. The patient was discharged on the 45th day. It is suggested that injection of minocycline might represent an effective and less invasive treatment option for postoperative severe bile leakage.</p>

Journal

  • Tando

    Tando 38 (1), 85-90, 2024-03-31

    Japan Biliary Association

Keywords

Details 詳細情報について

  • CRID
    1390581148794619776
  • DOI
    10.11210/tando.38.85
  • ISSN
    18836879
    09140077
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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