Development of Methodologies toward the Unified Synthesis of Ellagitannins
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- Ikeuchi Kazutada
- Graduate School of Pharmaceutical Sciences, Nagoya City University
Abstract
<p>Ellagitannins, a class of polyphenols with divergent structures, have attracted considerable attention from synthetic organic chemists. The basic structures in ellagitannins contain esters of D-glucose with galloyl or hexahydroxyldiphenoyl groups, as well as diaryl ether structures. Thus, the synthesis methodologies of such components have been developed by various groups, including our group. This review describes the synthetic methods reported by our group during 2017–2023, aimed at increasing the number of ellagitannins that can be chemically synthesized. In addition, recent related reports are introduced.</p>
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 72 (4), 349-359, 2024-04-01
The Pharmaceutical Society of Japan