Chronic Effects of Adaptive Servo-Ventilation Therapy on Mortality and the Urgent Rehospitalization Rate in Patients Experiencing Recurrent Admissions for Heart Failure ― A Multicenter Prospective Observational Study (SAVIOR-L) ―
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- Fukumoto Yoshihiro
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine
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- Tada Takeshi
- Cardiovascular Medicine, Kurashiki Central Hospital
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- Suzuki Hideaki
- Department of Cardiovascular Medicine, Tohoku University Hospital Department of Brain Sciences, Imperial College London
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- Nishimoto Yuji
- Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center
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- Moriuchi Kenji
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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- Arikawa Takuo
- Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine
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- Adachi Hitoshi
- Division of Cardiology, Gunma Prefectural Cardiovascular Center
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- Momomura Shin-ichi
- Department of Medicine, Saitama Citizens Medical Center
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- Seino Yoshihiko
- Medical Corporation Ryosyu-kai Nippon Medical School
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- Yasumura Yoshio
- Department of Cardiology, Amagasaki Chuo Hospital
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- Yokoyama Hiroyuki
- Yokoyama Medical Clinic
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- Hiasa Go
- Department of Cardiology, Ehime Prefectural Central Hospital
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- Hidaka Takayuki
- Department of Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University Department of Cardiology, Hiroshima Prefectural Hospital
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- Nohara Shoichiro
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine
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- Okayama Hideki
- Department of Cardiology, Ehime Prefectural Central Hospital
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- Tsutsui Hiroyuki
- School of Medicine and Graduate School, International University of Health and Welfare
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- Kasai Takatoshi
- Department of Cardiovascular Biology and Medicine and Cardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of Medicine
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- Takata Yoshifumi
- Department of Cardiology, Tokyo Medical University
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- Enomoto Mika
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine
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- Saigusa Yusuke
- Department of Biostatistics, Yokohama City University School of Medicine
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- Yamamoto Kouji
- Department of Biostatistics, Yokohama City University School of Medicine
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- Kinugawa Koichiro
- The Second Department of Internal Medicine, Faculty of Medicine, University of Toyama
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- Kihara Yasuki
- Department of Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University Kobe City Medical Center General Hospital
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<p>Background: This study investigated whether the chronic use of adaptive servo-ventilation (ASV) reduces all-cause mortality and the rate of urgent rehospitalization in patients with heart failure (HF).</p><p>Methods and Results: This multicenter prospective observational study enrolled patients hospitalized for HF in Japan between 2019 and 2020 who were treated either with or without ASV therapy. Of 845 patients, 110 (13%) received chronic ASV at hospital discharge. The primary outcome was a composite of all-cause death and urgent rehospitalization for HF, and was observed in 272 patients over a 1-year follow-up. Following 1:3 sequential propensity score matching, 384 patients were included in the subsequent analysis. The median time to the primary outcome was significantly shorter in the ASV than in non-ASV group (19.7 vs. 34.4 weeks; P=0.013). In contrast, there was no significant difference in the all-cause mortality event-free rate between the 2 groups.</p><p>Conclusions: Chronic use of ASV did not impact all-cause mortality in patients experiencing recurrent admissions for HF.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 88 (5), 692-702, 2024-04-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390581401102818304
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 033471877
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- PubMed
- 38569914
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 抄録ライセンスフラグ
- 使用不可