Clinical Outcomes of Treatment for Oral Cancer at Osaka Medical and Pharmaceutical University: A 24-year Experience

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  • 当科における口腔癌の治療成績―24年間の検討―
  • トウ カ ニ オケル コウクウ ガン ノ チリョウ セイセキ : 24ネンカン ノ ケントウ

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<p>We retrospectively analyzed the treatment results in 543 oral cancer patients who were admitted to our department between September 1999 and March 2023. The tongue was the most common primary subsite, followed by the gingiva and oral floor. Among the total of 543 cases of oral cancer, there were 132 clinical node-positive cases (24%). The overall 5-year disease-specific survival (DSS) rate was 71.8%, and the 5-year DSS rates in the stage I, II, III, and IV oral cancer cases were 91.5%, 81.2%, 62.1%, and 48.5% respectively. The 5-year DSS rates in the stage I, II, III, and IV tongue cancer cases were 91.4%, 80.6%, 59.5%, and 44.9%, respectively. The new N classification was more reliably associated with the survival as compared with previous N classifications in the tongue carcinoma cases. Among the 184 cases with T2 oral cancer, 77 (42%) were node-positive. An advanced T stage and a positive neck nodal status were significantly associated with poorer 5-year DSS rates.</p>

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