Changes in Burn Wound Surface and its Evaluation After Treatment with Nexobrid, a Necrotic Tissue Removal Agent for Burn Wounds

DOI

Bibliographic Information

Other Title
  • 熱傷創に対する新しい壊死組織除去剤ネキソブリッド<sup>®</sup>使用後の熱傷創面の変化とその評価

Description

<p> Objective: Nexobrid was launched in Japan on August 1, 2023, as a chemical debridement agent for burn wounds. We examined the subsequent treatment course of patients treated with Nexobrid, based on changes in the burn wound surface.<br> Method: We retrospectively examined image records and treatment course of patients who visited our hospital and were diagnosed with deep dermal burn (DDB) to deep burn (DB) and were administered Nexobrid.<br> Results: A total of 14 cases of DDB to DB, totaling 23 sites, were enrolled. Fourteen sites required conservative treatment and nine sites required surgical treatment.<br> We examined the wound surface color from the image records. We found that the subsequent treatment course could be predicted by classifying the changes into four major categories: 1. red (pink) , 2. white, 3. dark red, and 4. exposed fat. Furthermore, the dark red category was sub-classified into three subcategories based on subsequent changes.<br> Discussion: The European consensus guidelines classify wound surface changes into four major categories and outline the subsequent course. We found that dark red cases in our classification, which correspond to ‘3. Large diameter red circle or oval patterns’ in the European guidelines, show different changes compared to the other categories. Our findings suggest that by further subclassifying the changes in the dark red category into three subcategories, formulation of a more precise treatment plan is possible.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390583004894911744
  • DOI
    10.34366/jburn.50.3_96
  • ISSN
    24351571
    0285113X
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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