Novel Method for Risk Stratification of Major Adverse Clinical Events Using Pre- and Post-Ablation Left Atrial Volume Index in Patients With Persistent Atrial Fibrillation

DOI Web Site 参考文献26件
  • Ishiguchi Hironori
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital
  • Yoshiga Yasuhiro
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Shimizu Akihiko
    Department of Cardiology, Ube-Kohsan Central Hospital
  • Fukuda Masakazu
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Omuro Ayumi
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Hisaoka Masahiro
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Nakashima Yusuke
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Fujita Miho
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Hashimoto Shintaro
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Omuro Takuya
    Department of Medicine and Clinical Science, Faculty of Health Sciences, Yamaguchi University Graduate School of Medicine
  • Ariyoshi Toru
    Ultrasound Examination Center, Yamaguchi University Hospital
  • Kobayashi Shigeki
    Department of Therapeutic Science for Heart Failure in the Elderly, Yamaguchi University Graduate School of Medicine
  • Okamura Takayuki
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Sano Motoaki
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine

説明

<p>Background: The relationship between changes in the left atrial volume index (LAVI) post-catheter ablation (CA) and long-term prognostic events in patients with persistent atrial fibrillation (AF) remains unclear. We evaluated the incidence of major adverse clinical events (MACE), including all-cause death, unplanned heart failure hospitalization, and unplanned cardiovascular hospitalization using pre- and post-CA LAVI.</p><p>Methods and Results: We collected data retrospectively from 150 patients with persistent AF who underwent their first CA. LAVI was calculated during preprocedural echocardiography under AF rhythm (pre-CA LAVI) and 3 months post-CA under sinus rhythm (post-CA LAVI). The cumulative incidence of MACE was compared among 3 subgroups based on the cutoff values of pre-CA (45.5 mL/m2) and post-CA (46.5 mL/m2; both determined using the c-statistic) LAVI. The subgroup of a pre-CA LAVI >45.5 mL/m2with a post-CA LAVI >46.5 mL/m2(n=45) had a significantly higher MACE incidence compared with other subgroups (P=0.002). Multivariate analysis identified this subgroup as independently at higher risk for MACE. The subgroup of a pre-CA LAVI >45.5 mL/m2with a post-CA LAVI ≤46.5 mL/m2(n=49) had an incidence comparable with those with pre-CA LAVI ≤45.5 mL/m2(n=56) and exhibited a significantly greater reduction in LAVI than other subgroups did (P<0.001).</p><p>Conclusions: Combining pre-CA and post-CA LAVIs is valuable in stratifying long-term MACE development risk following CA.</p>

収録刊行物

  • Circulation Reports

    Circulation Reports 6 (10), 415-423, 2024-10-10

    一般社団法人 日本循環器学会

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