Successful treatment of chronic hepatitis C with crushed tablet for sofosbuvir/ledipasvir

DOI Web Site Web Site 9 References Open Access

Bibliographic Information

Other Title
  • ソホスブビル/レジパスビル配合錠の粉砕投与を行い著効が得られたC型慢性肝炎の1例
  • 症例報告 ソホスブビル/レジパスビル配合錠の粉砕投与を行い著効が得られたC型慢性肝炎の1例
  • ショウレイ ホウコク ソホスブビル/レジパスビル ハイゴウジョウ ノ フンサイ トウヨ オ オコナイ チョコウ ガ エラレタ Cガタ マンセイ カンエン ノ 1レイ

Search this article

Description

<p>A 65-year-old woman with early-onset Alzheimer's disease and type 2 diabetes mellitus received a house call from a medical practitioner. Antiviral therapy could be performed for chronic hepatitis C (genotype 2), and she visited our hospital. It was difficult for her to take tablets because of early-onset Alzheimer's disease; therefore, we provided crushed tablets of sofosbuvir/ledipasvir for 12 weeks. HCV-RNA in her blood showed negative conversion 8 weeks after treatment initiation, and SVR 12 was obtained.</p><p>In antiviral therapy against chronic hepatitis C, it is necessary to carefully consider adaptation when treatment is indicated when the patient finds it difficult to take tablets. However, internal treatment with crushed tablets is believed to be an option.</p><p>We report a case of antiviral treatment for chronic hepatitis C wherein it was difficult to take a tablet, and we experienced the case of a patient for whom treatment with crushed tablets was successful.</p>

Journal

  • Kanzo

    Kanzo 60 (9), 332-337, 2019-09-01

    The Japan Society of Hepatology

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top