Hierarchical structure of fluidic channels and their application to bio-devices

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  • 流体流路の階層サイズ構造とバイオデバイスへの応用
  • リュウタイ リュウロ ノ カイソウ サイズ コウゾウ ト バイオデバイス エ ノ オウヨウ

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Abstract

<p>Microfluidics has rapidly developed to realize ultra-small volumes (nL) and high speed (sec - min) chemical processes for analyses, synthesis and bio-experiments, by integrating various chemical operations into µm scale fluidic channels fabricated on a substrate. Recently, the research field has been extended to extended-nano fluidics exploiting 10-100nm fluidic channels of aL-fL volumes much smaller than a single cell and unique liquid properties. Novel chemical devices such as single cell/single molecule analyses and energy devices can be expected. For these purposes, new fundamental technologies to fabricate the ultra-small spaces, measure molecules, and investigate liquid properties and phenomena are required. Here we review the state-of-the-art technology and perspectives of this new science and engineering field.</p>

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  • Oyo Buturi

    Oyo Buturi 84 (10), 882-888, 2015-10-10

    The Japan Society of Applied Physics

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