Acute onset autoimmune hepatitis associated with secondary autoimmune hemolytic anemia

Sunaga Shogo, Okamura Yukishige, Horie Tomofumi, Kameyama Hisako, Teramoto Ken, Higashizawa Toshihiko, Sekine Chuuichi

doi:10.2957/kanzo.60.439

Bibliographic Information

Other Title

急性発症の自己免疫性肝炎に続発した自己免疫性溶血性貧血の一例
症例報告急性発症の自己免疫性肝炎に続発した自己免疫性溶血性貧血の一例
ショウレイホウコクキュウセイハッショウノジコメンエキセイカンエンニゾクハツシタジコメンエキセイヨウケツセイヒンケツノイチレイ

Search this article

Description

<p>A 52-year-old woman with Hashimoto's disease was admitted to our hospital following acute onset jaundice and liver dysfunction. We diagnosed her with autoimmune hepatitis and initiated prednisolone therapy. Subsequently, her liver dysfunction improved, while anemia of an uncertain cause progressed. Thus, we diagnosed concurrent autoimmune hemolytic anemia via a peripheral blood and bone marrow tests. The patient's liver dysfunction and anemia gradually improved with continuation of prednisolone. Although patients with autoimmune hepatitis may present with other autoimmune disorders due to the dysfunction of immunologic mechanisms, the concurrence of autoimmune hemolytic anemia is rare. Immunosuppressive treatment including steroid therapy is effective in cases with autoimmune hepatitis and autoimmune hemolytic anemia. This case presented findings of hemolytic anemia after liver dysfunction, suggesting a diagnosis of acute onset autoimmune hepatitis with secondary autoimmune hemolytic anemia.</p>

Journal

Kanzo

Kanzo 60 (11), 439-446, 2019-11-01

The Japan Society of Hepatology

Keywords

Details 詳細情報について

Export

Report a problem