Considerations in the Relationship Between Obstructive Sleep Apnea and Depression

DOI Web Site

Bibliographic Information

Other Title
  • 睡眠時無呼吸症候群とうつ病
  • 睡眠時無呼吸症候群とうつ病 : 両者の関連性を検討する
  • スイミンジ ムコキュウ ショウコウグン ト ウツビョウ : リョウシャ ノ カンレンセイ オ ケントウ スル
  • ～両者の関連性を検討する～

Search this article

Abstract

Obstructive sleep apnea (OSA) and depression may coexist in the same patient. In addition to the usual symptoms associated with OSA such as poor concentration, fatigue, excessive daytime sleepiness (EDS) and reduced　cognitive function, OSA can also cause depressive disorders. In a large−scale study of 18,980 representative adults from five　European countries, Ohayon et al. reported that 17.6% had both OSA and DSM−IV symptoms. Two randomly selected　long−term large−scale studies reported that the adjusted odds ratio of onset of depression in OSA patients was 1.8 times　(Peppard et al.) and 2.18 times (Chen et al.). If there is a strong relationship between them, the reduction of depressive　symptoms by CPAP therapy would be expected. In our hospital, 20 patients undergoing treatment for depression in　combination with OSA were followed up after OSA treatment. 14 of the 20 underwent CPAP therapy, and of 12 who　continued, 7 were able to reduce or stop their central nervous system medicines. Even with CPAP, OSA patients who exhibit excessive daytime sleepiness should consider the possible existence of depression. Likewise, patients with depression, who do not respond to treatment, should consider the possibility of OSA. The symptoms of OSA and depression can overlap in patients and have detrimental effects on each other.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top