Expression of activin receptors in the equine uteroplacental tissue: an immunohistochemical analysis
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- KIMURA Yuki
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan
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- SASAKI Motoki
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan
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- WATANABE Kenichi
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary, Hokkaido 080-8555, Japan
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- DHAKAL Pramod
- United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan Present address: Animal Science Research Center, Division of Animal Science, University of Missouri, Columbia, MO 65211, U.S.A.
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- SATO Fumio
- United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, Hokkaido 057-0171, Japan
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- TAYA Kazuyoshi
- Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan
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- NAMBO Yasuo
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary, Hokkaido 080-8555, Japan
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<p>Activin is secreted from equine uterine glands and plays important roles in establishment and maintenance of pregnancy in mares. This study aimed to localize activin receptors (ActRs) IA/B and IIA/B using immunohistochemistry in the uteroplacental tissues of seven pregnant Thoroughbred mares. At the time of tissue collection, the mares were at the following days of pregnancy: 88, 120, 161, 269, 290, 313, and 335 days. We fixed the uteroplacental tissues in 4% paraformaldehyde and obtained serial sections that were subsequently stained for analysis. All four isoforms of ActR were expressed in the uteroplacental tissues, including the endometrial epithelium, uterine glands, trophoblasts, and myometrium, throughout pregnancy. Our results suggested the potential role of activin in the uteroplacental tissues.</p>
収録刊行物
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- Journal of Equine Science
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Journal of Equine Science 29 (2), 33-37, 2018
日本ウマ科学会
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詳細情報 詳細情報について
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- CRID
- 1390845712972844928
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- NII論文ID
- 130007402972
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- NII書誌ID
- AA11010806
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- ISSN
- 13477501
- 13403516
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- NDL書誌ID
- 029149942
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
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- 使用不可