Investigation of Pharmacist Intervention on anti-cancer Chemotherapy Prescription

  • Tajima Hakuju
    Department of Pharmacy, International University of Health and Welfare Mita Hospital School of Pharmaceutical Sciences, International University of Health and Welfare
  • Uejima Kentaro
    Department of Pharmacy, International University of Health and Welfare Mita Hospital
  • Miura Ryoko
    Department of Pharmacy, International University of Health and Welfare Mita Hospital
  • Inoue Tadao
    Department of Pharmacy, International University of Health and Welfare Mita Hospital Graduate School of Pharmaceutical Sciences, International University of Health and Welfare

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Other Title
  • がん化学療法注射せんにおける疑義照会の分析
  • ガン カガク リョウホウ チュウシャ セン ニ オケル ギギ ショウカイ ノ ブンセキ

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Abstract

<p>The International University of Health and Welfare Mita Hospital realized that its injection ordering system is not organized properly. The prescriptions for anti-cancer chemotherapy injections submitted to the pharmacy department are handwritten, and a considerable number of prescriptions have omitted, wrong, inadequate, or suspicious descriptions prescribing unusual doses. Tasks such as inspecting injection prescription, filing drug administration histories, issuing transfusion labels, etc., all should be carried out by pharmacists. </p><p>In this study, referral prescriptions for anti-cancer chemotherapy injections between October 2008 and March 2009 were classified based on content and significance. The prescriptions were classified by contents into seven groups:i) dosage quantity, ii) dosage interval, iii) dosage time, iv) regimen, v) adjunctive therapy, vi) overlapped prescription, and vii) others. The prescriptions were also classified in regard to risk degree into 2 groups of A and B (A>B). </p><p>2390 prescriptions for anti-cancer chemotherapy injections were submitted during this study period. Of these, 173 (7.2%) contained suspicious references, while 110 (4.6%) had modifications to the prescription. Classified by content, group i) contained 62 prescriptions, group ii) 13 prescriptions, group iii) 21 prescriptions, group iv) 34 prescriptions, group v) 32 prescriptions, group vi) 6 prescriptions, and group vii) 5 prescriptions. Classified by significance, group A contained 55 prescriptions, and group B 118 prescriptions. </p><p>For prescriptions of anti-cancer chemotherapy injections the closest attention must be paid to prevent overdose. This study results confirmed the need for pharmacists to inspect prescriptions and references for suspicious content.</p>

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