Liver stiffness is a useful marker for assessing the therapeutic effect of angioplasty in Budd-Chiari syndrome: A case report

  • Nagahara Ran
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Matono Tomomitsu
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Koda Masahiko
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University Department of Internal Medicine, Hino Hospital
  • Matsuki Yukako
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Yamane Masashi
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Okamoto Toshiaki
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Miyoshi Kenichi
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Nagahara Takakazu
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Sugihara Takaaki
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Ohyama Kenji
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Okano Junichi
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Isomoto Hajime
    Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
  • Kodani Mika
    Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University
  • Yata Shinsaku
    Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University
  • Ohuchi Yasufumi
    Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University

Bibliographic Information

Other Title
  • 肝硬度が血管形成術治療効果判定に有用であったBudd-Chiari症候群の1例
  • 症例報告 肝硬度が血管形成術治療効果判定に有用であったBudd-Chiari症候群の1例
  • ショウレイ ホウコク カン コウド ガ ケッカン ケイセイジュツ チリョウ コウカ ハンテイ ニ ユウヨウ デ アッタ Budd-Chiari ショウコウグン ノ 1レイ

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Abstract

<p>A 32-year-old Japanese woman was diagnosed with Budd-Chiari syndrome with complete obstruction of the right and the middle hepatic vein as well as severe stenosis in the left hepatic vein. She had esophageal varices (F2) and low platelet counts (10.7 × 104/mm3). She underwent percutaneous transluminal angioplasty (PTA) for the left hepatic vein. Liver stiffness was decreased from 66.4 kPa before PTA to 16.8 kPa after 3 h and 10.4 kPa after 4 months with an improvement in the esophageal varices (F0) and platelet count (16.5 × 104/mm3). Furthermore, the serum level of hyaluronic acid decreased from 76 ng/ml before PTA to <9 ng/ml after 4 months. To our knowledge, this is the first case wherein liver stiffness was able to reflect hepatic congestion and helped monitor the therapeutic effect in Budd-Chiari syndrome.</p>

Journal

  • Kanzo

    Kanzo 59 (10), 563-570, 2018-10-20

    The Japan Society of Hepatology

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