A Case of Merkel Cell Carcinoma Arising on the Buttock

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  • ICHIKI Toshio
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • TSUJI Gaku
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University Research and Clinical Center for Yusho and Dioxin, Kyushu University Hospital
  • NAGAE Kounosuke
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • WADA Maiko
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • MASUDA Teiichi
    Tenjin Plastic & Aesthetic Surgery Clinic
  • NAGASE Koutaro
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • UCHI Hiroshi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • FURUE Masutaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University Research and Clinical Center for Yusho and Dioxin, Kyushu University Hospital

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Other Title
  • 臀部に発症した Merkel 細胞癌の 1 例
  • 症例 臀部に発症したMerkel細胞癌の1例
  • ショウレイ デンブ ニ ハッショウ シタ Merkel サイボウガン ノ 1レイ

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<p>An 81-year-old female noticed a subcutaneous nodule on her left buttock almost 1 year before her first visit to us. Because of its rapid growth, the lesion was resected. On histological examination, a proliferation of small round tumor cells was observed in the deep dermis and the subcutaneous tissue. Nuclear atypia and mitotic figures were also detected in the tumor cells. The tumor cells were positive for cytokeratin 20 and chromogranin A. An analysis by PET-CT scanning showed no other systemic involvement, indicating the diagnosis of primary Merkel cell carcinoma arising on the buttock. We performed an additional wide resection. However, a left inguinal lymphadenopathy was noticed 6 months later, which was histologically diagnosed as a lymph node metastasis of Merkel cell carcinoma. A subsequent left inguinal lymph node dissection revealed no residual Merkel cell carcinoma and the patient has been free from recurrence for 6 months after the final operation. Merkel cell carcinoma preferentially develops on sun-exposed areas and its occurrence on the buttock is rare.</p>

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