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Small Cell Lung Cancer with Sarcoidosis in Spontaneous Remission: A Case Report
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- Sasaki Yumeka
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Koga Yasuhiko
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Kasahara Norimitsu
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Hachisu Yoshimasa
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Murata Keisuke
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Tsurumaki Hiroaki
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Yatomi Masakiyo
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Tsukagoshi Yusuke
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Sawada Yuri
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Sakurai Reiko
- Oncology Center, Gunma University Graduate School of Medicine
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- Ono Akihiro
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Sunaga Noriaki
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Kaira Kyoichi
- Department of Oncology Clinical Development, Gunma University Graduate School of Medicine
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- Hirato Junko
- Department of Pathology, Gunma University Hospital
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- Maeno Toshitaka
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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- Dobashi Kunio
- Gunma University Graduate School of Health Sciences
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- Hisada Takeshi
- Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
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Description
<p>A 69-year-old woman was diagnosed with sarcoidosis, which was not treated with corticosteroid therapy. Her levels of angiotensin converting enzyme decreased significantly over 4 years and a mass lesion was detected near the lower part of her left main bronchus, and diagnosed as small cell lung cancer (SCLC). Treatment of the SCLC with a series of chemotherapeutic agents produced excellent results. The pulmonary sarcoidosis did not show any deterioration despite the frequent use of amrubicin, which is known to be a cause of interstitial pneumonia. This is a case report of SCLC complicated with sarcoidosis in a stage of spontaneous remission, possibly suggesting an association between sarcoidosis and tumor immunity, since recent reports have suggested that immune checkpoint inhibitors might be involved in the development of sarcoidosis.</p>
Journal
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- Journal of Nippon Medical School
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Journal of Nippon Medical School 85 (5), 291-296, 2018-10-15
The Medical Association of Nippon Medical School
