Small Cell Lung Cancer with Sarcoidosis in Spontaneous Remission: A Case Report

  • Sasaki Yumeka
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Koga Yasuhiko
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Kasahara Norimitsu
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Hachisu Yoshimasa
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Murata Keisuke
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Tsurumaki Hiroaki
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Yatomi Masakiyo
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Tsukagoshi Yusuke
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Sawada Yuri
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Sakurai Reiko
    Oncology Center, Gunma University Graduate School of Medicine
  • Ono Akihiro
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Sunaga Noriaki
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Kaira Kyoichi
    Department of Oncology Clinical Development, Gunma University Graduate School of Medicine
  • Hirato Junko
    Department of Pathology, Gunma University Hospital
  • Maeno Toshitaka
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine
  • Dobashi Kunio
    Gunma University Graduate School of Health Sciences
  • Hisada Takeshi
    Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine

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説明

<p>A 69-year-old woman was diagnosed with sarcoidosis, which was not treated with corticosteroid therapy. Her levels of angiotensin converting enzyme decreased significantly over 4 years and a mass lesion was detected near the lower part of her left main bronchus, and diagnosed as small cell lung cancer (SCLC). Treatment of the SCLC with a series of chemotherapeutic agents produced excellent results. The pulmonary sarcoidosis did not show any deterioration despite the frequent use of amrubicin, which is known to be a cause of interstitial pneumonia. This is a case report of SCLC complicated with sarcoidosis in a stage of spontaneous remission, possibly suggesting an association between sarcoidosis and tumor immunity, since recent reports have suggested that immune checkpoint inhibitors might be involved in the development of sarcoidosis.</p>

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  • 日医大誌

    日医大誌 85 (5), 291-296, 2018-10-15

    日本医科大学医学会

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