TUMOR INVASION TO THE ARTERIES FEEDING THE GALLBLADDER AS A NOVEL RISK FACTOR FOR CHOLECYSTITIS AFTER METALLIC STENT PLACEMENT IN DISTAL MALIGNANT BILIARY OBSTRUCTION
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- SOGABE Yuko
- Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine. Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KODAMA Yuzo
- Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine.
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- HONJO Hajime
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- AOYAMA Ikuo
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MURAMOTO Yuya
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KOGA Eri
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- YANAIDANI Takafumi
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KAWAI Munenori
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- YOSHIKAWA Teppei
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MATSUMOTO Shimpei
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MATSUMOTO Astushi
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MORI Yoshiharu
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- ONO Chikage
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- NISHIDA Miyu
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- NISHIDA Yoshihiro
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MIKAMI Takao
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MATSUNAGA Yasuhiro
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MIYAMOTO Yukiko
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KITAMI Motoya
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- NISHIKAWA Koji
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KONDO Masahiko
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- MIYAKE Naoki
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- KAWANAMI Chiharu
- Department of Gastroenterology and Hepatology, Otsu Red Cross Hospital.
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- SENO Hiroshi
- Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine.
Bibliographic Information
- Other Title
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- 胆嚢栄養動脈への腫瘍浸潤は遠位部悪性胆道狭窄に対するMetallic Stent留置後胆嚢炎の危険因子である
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Abstract
<p>Background and Aim: Cholecystitis is a major complication after self-expandable metallic stent (SEMS) placement for malignant biliary obstruction. Ischemia is one of the risk factors for cholecystitis, but little is known about the influence of tumor invasion to the feeding artery of the gallbladder on the onset of cholecystitis after SEMS placement. The aim of the present study was to identify risk factors for cholecystitis after SEMS placement. </p><p>Methods: Incidence and nine predictive factors of cholecystitis were retrospectively evaluated in 107 patients who underwent SEMS placement for unresectable distal malignant biliary obstruction at Kyoto University Hospital and Otsu Red Cross Hospital between January 2012 and June 2016.</p><p>Results: Cholecystitis occurred in 13 of 107 patients (12.1%) after SEMS placement during the median follow-up period of 262 days. Univariate analyses showed that tumor invasion to the feeding artery of the gallbladder and tumor involvement to the orifice of the cystic duct were significant predictors of cholecystitis (P=0.001 and P<0.001). Multivariate analysis confirmed that these two factors were significant and independent risks for cholecystitis with odds ratios of 22.13 (95% CI, 3.57-137.18; P=0.001) and 25.26 (95% CI, 4.12-154.98; P<0.001), respectively.</p><p>Conclusions: This study showed for the first time that tumor invasion to the feeding artery of the gallbladder as well as tumor involvement to the orifice of the cystic duct are independent risk factors for cholecystitis after SEMS placement.</p>
Journal
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- GASTROENTEROLOGICAL ENDOSCOPY
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GASTROENTEROLOGICAL ENDOSCOPY 61 (1), 71-80, 2019
Japan Gastroenterological Endoscopy Society
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Details 詳細情報について
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- CRID
- 1390845713038753024
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- NII Article ID
- 130007569115
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- ISSN
- 18845738
- 03871207
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed