Hypopituitarism associated with autoimmune pancreatitis: a case report

  • IKEDA Chisaki
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • MAKINO Naohiko
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • ANDO Yoshiaki
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • MATSUDA Akiko
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • KAKIZAKI Yasuharu
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • ISHIZAWA Tetsuya
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • SAITO Yoshihiko
    Department of Gastroenterology, Faculty of Medicine, Yamagata University
  • YAMAKAWA Mitsunori
    Department of Pathological Diagnostics, Faculty of Medicine, Yamagata University
  • KAMEDA Wataru
    Third Department of Medicine, Faculty of Medicine, Yamagata University
  • UENO Yoshiyuki
    Department of Gastroenterology, Faculty of Medicine, Yamagata University

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Other Title
  • 自己免疫性膵炎に併発した下垂体機能低下の1例

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Abstract

<p>We herein report the case of a 64-year-old male patient with hypopituitarism associated with autoimmune pancreatitis (AIP). The patient was previously diagnosed with AIP based on the presence of a swollen pancreas, elevated serum immunoglobulin G4, and narrowing of the pancreatic duct by imaging. Magnetic resonance imaging revealed a pituitary stem tumor, and loading test showed a decrease in the function of the anterior lobe suggesting severe failure of growth hormone secretion. Treatment with steroids was effective in reducing the pituitary lesion and improving the function of the anterior lobe. The present case illustrates the importance of pituitary function evaluation before steroid treatment in patients with AIP.</p>

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