Effective Timing of Curcumin Ingestion to Attenuate Eccentric Exercise-Induced Muscle Soreness in Men
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- TANABE Yoko
- Department of Sport Research, Japan Institute of Sports Sciences
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- CHINO Kentaro
- Department of Sport Research, Japan Institute of Sports Sciences
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- SAGAYAMA Hiroyuki
- Japan Society for the Promotion of Science
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- LEE Hyun Jin
- Science Group, Theravalues Corporation
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- OZAWA Hitomi
- Science Group, Theravalues Corporation
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- MAEDA Seiji
- Faculty of Health and Sport Sciences, University of Tsukuba
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- TAKAHASHI Hideyuki
- Department of Sport Research, Japan Institute of Sports Sciences
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説明
<p>Curcumin is known to have potent anti-inflammatory effects. We have reported that acute curcumin ingestion attenuates eccentric exercise-induced muscle damage. This study aimed to examine the effect of curcumin ingestion timing (before or after exercise) on the changes in muscle damage markers after eccentric exercise. In this randomized, single-blind, parallel design study, 24 healthy young men performed 30 maximal isokinetic (120º/s) eccentric contractions of the elbow flexors using an isokinetic dynamometer. Subjects were randomly assigned to ingest 180 mg/d of oral curcumin either 7 d before (PRE) or 4 d after exercise (POST) or 180 mg/d of oral placebo 4 d after exercise (CON). The maximal voluntary contraction (MVC) torque of the elbow flexors, elbow joint range of motion (ROM), muscle soreness, and serum creatine kinase (CK) activity were measured before, immediately after, and 1-4 d after exercise. Changes in these variables were compared over time. In the POST group, ROM were higher at 3-4 d and muscle soreness was lower at 3 d after exercise compared with the CON group (p<0.05). However, in the PRE group, there were no significant differences compared with the CON group in changes in ROM and muscle soreness. Meanwhile, there were no significant differences among the groups in terms of changes in MVC torque and serum CK activity. Our results suggest that curcumin ingestion after exercise had a more beneficial effect in attenuating muscle soreness.</p>
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 65 (1), 82-89, 2019-02-28
一般財団法人 学会誌刊行センター
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詳細情報 詳細情報について
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- CRID
- 1390845713054887808
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- NII論文ID
- 130007605073
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 029535793
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- PubMed
- 30814417
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可