Basic Study for Tissue Characterization with Dual Energy Computed Tomography

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  • Dual-energy CT による組織成分抽出の基礎研究
  • Dual-energy CTによる組織成分抽出の基礎研究 : Spectral factor分解の精度向上へ向けて
  • Dual-energy CT ニ ヨル ソシキ セイブン チュウシュツ ノ キソ ケンキュウ : Spectral factor ブンカイ ノ セイド コウジョウ エ ムケテ
  • Spectral factor 分解の精度向上へ向けて
  • For the Feasibility of Spectral Factor Approach

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Abstract

The spectral factor approach for material-decomposition proposed by Brooks was examined by analytical dual-energy CT computer simulations. Parametrization of the linear attenuation coefficient for 15 tissue-equivalent inserts in a numerical water phantom was done. Scans of the numerical phantom were acquired at 80 kVp and additional tin filtration at 140 kVp tube from which effective atomic number, (Z*), and electron density, (ρe), of each insert were derived. For the theoretical polychromatic fan-beam projection, the errors on Z* and ρe extraction were more than 2.5% and 4.5% respectively. However, by applying the calibrated spectral factor with high Z*, the energy dependence of measured tissue parameters are canceled by beam hardening phenomenon and the errors on Z* and ρe extraction were diminished less than ±2% and ±0.5%. This result indicated that the spectral factor approach provides a means for improving the accuracy of the characterization of tissues in dual-energy computed tomographic imaging.

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